Motif Neurotech Wins Award to Develop Therapeutic Brain-Computer Interface

The interface consists of a network of millimeter-sized wireless implants placed in the skull

Motif Neurotech Dot Neural Device
Motif Neurotech

Motif Neurotech, a Houston-based neurotechnology company, announced its selection by UK’s Advanced Research and Invention Agency (ARIA) for multi-million dollar award to support its development of a therapeutic brain-computer interface (BCI) technology to treat cognitive and psychiatric conditions. The award will fund development of a network of neural devices designed to monitor and regulate mental and cognitive states without brain surgery. The award is part of ARIA’s Precision Neurotechnologies program, led by program director Jacques Carolan.

The technology planned with this funding could have an impact on the treatment of cognitive, neurological, and psychiatric conditions by helping to regulate brain states associated with mood, attention, and sleep. Part of this award will focus on making the technology more accessible to patients by designing implantation to be simple, rapid, and low risk. This work will also focus on improving the specificity of brain stimulation by targeting specific cell types, which could lead to more effective treatments with fewer side effects.

The interface consists of a network of millimeter-sized wireless implants placed in the skull during a 20-minute procedure and designed to be cosmetically invisible. Without contacting the brain, each device will provide cell-type specific stimulation and electrical recording. Arrays like these could span the entire cortical surface, enabling regulation of brain-wide circuits in a way that meets the needs of each patient.

Motif Neurotech will collaborate with research partners under this grant to develop the technology. MintNeuro, a UK startup, will help develop custom integrated circuits that will help to miniaturize the implants. Kaiyuan Yang, an associate professor of Electrical and Computer Engineering department at Rice University will help design circuits for efficient wireless data and power transfer. The Robinson Lab at Rice University will support system integration and testing. Valentin Dragoi, a professor of electrical and computer engineering at Rice, the Rosemary and Daniel J. Harrison III Presidential Distinguished Chair in Neuroprosthetics at Houston Methodist and professor of neuroscience at Weill Cornell Medical College will lead the preclinical animal studies.

The ARIA award is a major milestone for Motif Neurotech and a significant vote of confidence in the company’s technology. This funding will help Motif advance its mission of creating neural devices to help everyone with mental or cognitive disorders live a better life.

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