SolasCure, a biotechnology company developing a novel treatment to transform chronic wound care, and the U.S. Army Institute of Surgical Research today announced a research collaboration to evaluate SolasCure’s investigational product, Aurase Wound Gel, as a means for managing combat wounds. Aurase Wound Gel is a hydrogel releasing tarumase, a recombinant enzyme derived from medical maggots, which is currently being developed to promote wound healing through debridement and wound bed preparation.
In partnership with USAISR, two non-clinical development projects will be initiated to assess the potential for the enzymatic debridement properties of Aurase Wound Gel to reduce wound biofilm production and/or bioburden in conjunction with standard-of-care in prolonged field care scenarios. Opportunistic pathogens such as Pseudomonas aeruginosa and MRSA complicate wound care by producing toxins and enzymes that damage tissue. They often lead to chronic infections that are hard to eradicate due to biofilm formation and antibiotic resistance. The projects aim to specifically target combat-relevant persistent strains of Pseudomonas aeruginosa and MRSA both in vitro and in vivo.
AISR is recognized as the U.S. Army’s premier research laboratory for improving the care of combat casualties. The collaboration aims to generate non-clinical data that could be used as a first step to validate the use of Aurase Wound Gel in highly challenging combat conditions.
