BEVERLY, Mass. - Trauma doesn't wait, and neither should treatment. Despite advancements in emergency medical services, 42% of hemorrhaging car crash victims die after help arrives, not due to delays, but because life-saving blood products like plasma are unavailable at the point of care. Without blood products in ambulances, helicopters, or rural clinics, many patients don't survive.
Velico recently completed its first-in-human Phase I multi-center clinical trial of FrontlineODP Spray Dried Plasma in healthy volunteers. The dose-escalation study with a randomized, crossover cohort demonstrated the safety of the spray dried plasma, with no serious adverse events or safety signals reported.
Dr. Mark Popovsky, Chief Medical Officer at Velico, said, "This trial marks the beginning of a new era in plasma therapy. A plasma product that's safe, portable, and transfusion-ready in just 2.5 minutes could transform how trauma is treated - both on the battlefield and in civilian emergencies."
The clinical success comes at a time when the global supply of dried plasma is critically low - fewer than 30,000 units exist worldwide, and production is highly centralized in a few countries. This scarcity threatens national and global health security, particularly in the face of increasing conflict, natural disasters, and mass casualty events.
FrontlineODP Spray Dried Plasma is specifically designed to address this gap. It is produced through a decentralized model, ensuring accessibility where it's needed most. The product is shelf-stable for up to 24 months, ultra-lightweight for easy transport and rapid field deployment, and can be quickly reconstituted for immediate use in emergencies.
These features would enable governments and healthcare systems to build resilient, decentralized plasma reserves, improving emergency readiness across both civilian and military sectors.
Richard Meehan, CEO of Velico, said, "Current limited supply of dried plasma requires a new solution. This is about preparedness and sovereignty. Nations need the ability to invest in domestic capacity now, or they may face being unprepared when the next crisis hits."
