Elucid said it received FDA clearance for its PlaqueIQ imaging analysis software to help physicians diagnose cardiovascular disease (CVD). PlaqueIQ is non-invasive software that can quantify and classify plaque morphology based on ground-truth histology.
PlaqueIQ uses first-line diagnostic CCTA and develops interactive reports to help physicians virtually “see” plaque at the vessel level. With its basis in histology, the software is able to non-invasively quantify and characterize non-calcified plaque and its components such as lipid-rich necrotic core (LRNC), giving potential insights into high-risk plaques that are key drivers of risk of heart attack and stroke. In addition, use of the software has the potential to enable earlier identification of higher-risk plaque before presence of symptoms or major adverse events.
Physicians simply send patient images to Elucid with a single mouse click. Then Elucid applies PlaqueIQ’s image-restoration algorithms to the file to mitigate motion and calcium blooming artifacts. Specially trained analysts segment the data creating a 3D model of the patient’s coronary arteries. The software then identifies, classifies and quantifies tissue structure and composition.
Elucid is currently performing beta testing on PlaqueIQ and anticipates making the software available for limited release later in Q4 2024. The company is also pursuing an indication for non-invasive measurement of fractional flow reserve (FFRCT™), uniquely derived from its PlaqueIQ technology, to measure coronary blockages and the extent of ischemia.
