PCI Pharma Services, an integrated contract development and manufacturing organization (CDMO) focused on biologic and small molecule therapies, is making a series of infrastructure investments to expand its sterile fill-finish and advanced drug delivery capabilities.
PCI’s plan includes a $100 million project at its San Diego campus featuring a high-speed isolator filling line for ready-to-use (RTU) prefilled syringes and cartridges. Scheduled to be operational in the first half of 2028, the line will more than double the site's existing syringe and cartridge filling capacity. It will be PCI’s second isolator fill-finish line in San Diego, which currently supports and manufactures over 45 FDA-approved products. The campus also hosts large-scale aseptic filling for prefilled syringes and cartridges, alongside specialized capabilities in oligonucleotides, peptides, complex formulations and lyophilization for injectables such as nanoparticles, mRNA, mAbs, proteins, and highly potent products.
Meanwhile, PCI’s Bedford, New Hampshire campus is commissioning a GMP-ready bespoke isolator vial and lyophilization line that, upon commencing full-scale production this month, will be capable of producing batch sizes of up to 300,000 vials at 400 units per minute, for an annual total of 33 million. The campus also will commission a customer-dedicated high-potent sterile fill-finish line.
In both San Diego and Bedford, PCI also has invested in automated visual inspection (AVI) systems for sterile fill-finish applications. In total, PCI's US-based AVI infrastructure supports more than 70 million prefilled syringes and cartridges and 40 million vials per year, meeting the exacting standards of global pharmaceutical manufacturers.
